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. 2021 Nov 11;21:1199. doi: 10.1186/s12885-021-08952-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Association between ROR2 mRNA/protein expression level and clinicopathological parameters in the ICGC-PACA-AU,TCGA-PAAD and CPTAC-PDAC cohorts. A. No significant difference in ROR2 expression was observed between low and high tumour grade. B. ROR2 mRNA expression was not associated with stage, ROR2 protein expression was significantly different between low and high stage (p = 0.010). C. High ROR2 mRNA expression level was associated with better overall survival (p = 0.023) in the ICGC-PACA-AU cohort. D. High ROR2 mRNA expression level was associated with better overall survival (p = 0.008) in the TCGA-PAAD cohort. E. ROR2 mRNA was not associated with overall survival in the CPTAC-PDAC cohort. F. ROR2 protein was not associate with overall survival in the CPTAC-PDAC cohort.*Significance at p < 0.05 level