Table 1.
Clinical and laboratory characteristics of patients with peripheral artery disease (PAD group) and controls (CO group) at baseline
| PAD group (n=168) | CO group (n=74) | P value | |
|---|---|---|---|
| Age (y) | 76 ± 11 | 70 ± 10 | 0.223 |
| Males, n (%) | 141 (83.9) | 60 (81) | 0.929 |
| Smoking, n (%) | 43 (25.6) | 13 (17.6) | < 0.001 |
| Hypertension, n (%) | 125 (74.4) | 13 (17.6) | < 0.001 |
| Dyslipidemia, n (%) | 162 (96.4) | 35 (47.3) | < 0.001 |
| Statins, n (%) | 160 (95.2) | 19 (25.7) | < 0.001 |
| ABI | 0.48 (0.09) | 1.1 (0.1) | < 0.001 |
| Diabetes, n (%) | 68 (36.9) | 7 (9.5) | < 0.001 |
| BMI (kg/m2) | 27.98 ± 3.22 | 26.9 ± 4.32 | 0.212 |
| SBP (mmHg) | 139 ± 21 | 125 ± 12 | < 0.001 |
| DBP (mmHg) | 85 ± 9 | 78 ± 8 | 0.405 |
| Creatinine (mg/dl) | 1.61 ± 0.4 | 1.1 ± 0.3 | 0.112 |
| TChol (mg/dl) | 183 ± 54 | 162 ± 41 | 0.105 |
| HDL-C (mg/dl) | 41 ± 8 | 49 ± 13 | 0.013 |
| LDL-C (mg/dl) | 117 ± 43 | 92 ± 22 | 0.072 |
| TG (mg/dl) | 122 ± 64 | 106 ± 33 | 0.199 |
| FPG (mg/dl) | 145 ± 35 | 100 ± 17 | < 0.001 |
| HbA1c (%)a | 7.3 ± 1.4 | – | – |
| WBC (cells/µL) | 10,984 ± 2998 | 6234 ± 2109 | < 0.001 |
| hsCRP (mg/L) | 7.64 ± 2.26 | 1.12 ± 0.42 | < 0.001 |
| RBP-4 (mg/L) | 43.33 ± 18.88 | 15.11 ± 4.45 | < 0.001 |
| Adiponectin (mg/L) | 6.53 ± 2.45 | 12.33 ± 2.1 | < 0.001 |
Data are expressed as means ± SD. n, number of patients; BMI, body-mass index; SBP, systolic blood pressure, DBP, diastolic blood pressure; TChol, total cholesterol; TG, triglycerides; FPG, fasting plasma glucose; WBC, white blood cells; hsCRP, high-sensitivity C-Reactive Protein
aHbA1c was measured only in diabetic patients