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. 2021 Oct 28;12:705086. doi: 10.3389/fimmu.2021.705086

Figure 6.

Figure 6

Preliminary experimental verification of PMEPA1 signature in BLCA. (A) Immunohistochemical staining of PMEPA1 and macrophages (CD68) in the low- and high-PMEPA1 group at 100X and 200X magnification. Serial sections were used for the two antibody staining. (B) The expression of PMEPA1 in BLCA tissues of different T-stage in three datasets [Xiangya cohort (n=60), TCGA (n=408), GSE32894 (n=308)]. The horizontal axis represents different T-stages, and the vertical axis represents the expression level of PMEPA1, (C) The level of TAMs infiltration investigated for the low- and high-PMEPA1 group in three datasets above. The vertical axis represents the infiltration level of TAMs, (D) The patient clinical parameters and their association with PMEPA1 expression in three datasets above. The asterisks indicated a statistically significant p-value (*P < 0.05; **P < 0.01; ****P < 0.0001; ns, P ≧ 0.05).