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. Author manuscript; available in PMC: 2021 Nov 11.
Published in final edited form as: Dev Dyn. 2019 Sep 10;248(12):1195–1210. doi: 10.1002/dvdy.106

Figure 8. Hyaluronidase treatment can rescue the bmp4 expression pattern in Ztmem2 mutants.

Figure 8.

Expression of bmp4 in wt (A, C) and Ztmem2 mutant (B, D) embryos at 48 hpf, as in Fig. 2. Pericardial injection of PBS did not alter the bmp4 expression pattern in wt (A) or Ztmem2 mutant (B) embryos (compare to Fig. 2A,B). In contrast, pericardial injection of hyaluronidase restored the concentrated expression of bmp4 at the AVC in the majority of the injected Ztmem2 mutants (D, arrowheads; Table 3), but did not affect the bmp4 expression pattern in the majority of the injected wt sibling embryos (C, arrowheads; Table 3).