Table 3.

Factors associated with meaning in life scores

		Univariate Estimate (95%CI)	P-value	Multivariate Estimate (95%CI)	P-value
All sites
Age		0.02 (−0.01, 0.04)	0.09
Sex	Female vs Male	−0.01 (−0.56, 0.54)	0.97
Marital status	Single vs Married	−1.41 (−2.22, −0.61)	<.001
	Divorced vs Married	−0.76 (−1.49, −0.03)	0.04
Country	Brazil vs US	−0.24 (−1.01, 0.53)	0.54	0.01 (−0.77, 0.78)	0.99
	Chile vs US	−0.23 (−1.20, 0.74)	0.64	0.03 (−0.85, 0.90)	0.96
	India vs US	−1.59 (−2.78, −0.41)	0.01	−0.45 (−1.62, 0.73)	0.46
	Jordan vs US	0.19 (−0.50, 0.88)	0.59	−0.06 (−0.78, 0.65)	0.87
Education level	Some college up to bachelors degree vs illiterate or high school or less	0.74 (0.17, 1.31)	0.006
	Advanced degree vs illiterate or high school or less	1.29 (0.31, 2.26)
Cancer class	Gastrointestinal vs Breast	−0.18 (−1.05, 0.69)	0.68
	Genitourinary vs Breast	0.27 (−0.78, 1.32)	0.62
	Gynecologic vs Breast	−0.15 (−1.26, 0.97)	0.80
	Head and neck vs Breast	−1.01 (−2.1, −0.08)	0.07
	Hematologic vs Breast	−0.23 (−1.69, 1.23)	0.76
	Non-small cell lung vs Breast	−5.36 (−12.72, 1.99)	0.15
	Other vs Breast	−0.29 (−1.32, 0.74)	0.58
	Respiratory vs Breast	0.50 (−0.44, 1.43)	0.30
Stage of cancer	Advanced vs Metastatic	−0.36 (−2.22, 1.51)	0.71
	Locally advanced vs Metastatic	−0.68 (−1.55, 0.20)	0.13
CAGE		−0.38 (−0.65, −0.12)	0.005
Pain		−0.16 (−0.25, −0.07)	0.001
Fatigue		−0.11 (−0.21, −0.02)	0.023
Nausea		0.00 (−0.10, 0.10)	0.936
Depression		−0.45 (−0.54, −0.36)	<.001	−0.26 (−0.35, −0.16)	<.001
Anxiety		−0.36 (−0.44, −0.27)	<.001
Drowsiness		−0.15 (−0.24, −0.06)	0.002
Appetite		−0.08 (−0.17, 0.02)	0.101
Dyspnea		−0.14 (−0.23, −0.05)	0.004
Sleep		−0.20 (−0.28, −0.11)	<.001
Spiritual Pain		−0.41 (−0.50, −0.33)	<.001	−0.19 (−0.28, −0.09)	<.001
Financial Distress		−0.31 (−0.39, −0.23)	<.001
Financial Impact		−0.34 (−0.42, −0.26)	<.001	−0.16 (−0.24, −0.08)	<.001
Optimism		0.46 (0.35, 0.58)	<.001	0.33 (0.20, 0.46)	<.001