Table 1.
Baseline demographics, clinical characteristics, and randomization status of the study sample
| Variables | All (n=71) |
No Delirium (n=45) |
Delirium (n=26) |
P-value |
|---|---|---|---|---|
| Demographics | ||||
| Age, median (IQR) | 62.6 (52.9, 69.3) | 61.7 (52.1, 67.9) | 65.9 (57.8, 70.6) | 0.147 |
| Female, n (%) | 14 (19.7%) | 7 (15.6%) | 7 (27.9%) | 0.354 |
| African-American, n (%) | 1 (1.4%) | 0 (0.0%) | 1 (3.8%) | 0.366 |
| Education | 0.738 | |||
| High School Graduate, n (%) | 40 (58.0%) | 27 (61.4%) | 13 (52.0%) | |
| Some College, n (%) | 17 (24.6%) | 10 (22.7%) | 7 (28.0%) | |
| Bachelor’s Degree or more, n (%) | 12 (17.4%) | 7 (15.9%) | 5 (20.0%) | |
| Clinical and Functional Characteristics | ||||
| Mechanically Ventilated, n (%) | 68 (95.8%) | 43 (95.6%) | 25 (96.2%) | 1.000 |
| APACHE II, median (IQR) | 18.0 (15.0, 25.0) | 17.0 (13.0, 24.0) | 24.0 (18.0, 27.0) | 0.012 |
| Charlson Comorbidity Index, median (IQR) | 3.0 (2.0, 3.0) | 2.0 (2.0, 3.0) | 3.0 (2.0, 5.0) | 0.119 |
| Activities of Daily Living (ADL), median (IQR) | 6.0 (6.0, 6.0) | 6.0 (6.0, 6.0) | 6.0 (6.0, 6.0) | 0.469 |
| Instrumental Activities of Daily Living (IADL), median (IQR) | 8.0 (7.0, 8.0) | 8.0 (7.0, 8.0) | 8.0 (7.0, 8.0) | 0.871 |
| ASA Class | 1.000 | |||
| ASA I, n (%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |
| ASA II, n (%) | 1 (1.4%) | 1 (2.2%) | 0 (0.0%) | |
| ASA III, n (%) | 70 (98.6%) | 44 (97.8%) | 26 (100.0%) | |
| Esophagectomy Technique | 1.000 | |||
| Ivor Lewis, n (%) | 63 (88.7%) | 40 (88.9%) | 23 (88.5%) | |
| Other, n (%) | 8 (11.3%) | 5 (11.1%) | 3 (11.5%) | |
| Randomization | ||||
| Intervention, n (%) | 34 (47.9%) | 25 (55.6%) | 9 (34.6%) | 0.139 |
ASA: American Society of Anesthesiologists; APACHE II: Acute Physiology and Chronic Health Evaluation