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. 2021 Oct 25;13(21):5346. doi: 10.3390/cancers13215346
0-D No Dimension
1-D One Dimension
2-D Two-Dimension
ABC ATP-Binding Cassette
ABCB1 ABC Sub-Family B Member 1
ABCC1 ABC transporter C1
ABCG2 ABC transporter G2
ATM Ataxia-Telangiectasia Mutated
ATR Ataxia–Telangiectasia and RAD3-Related
AUC Area Under The Curve
BAK Bcl-2 Homologous Antagonist Killer
BAX Bcl-2-Associated X Protein
BCL B cell lymphoma
BCRP Breast Cancer Resistance Protein
BH3 Bcl-2 Homology 3
BIND-014 PSMA-Targeted Docetaxel Nanoparticles
CDK Cyclin-Dependent Kinase
Chk2 Checkpoint Kinase 2
CL Clearance
Cmax Peak Drug Concentration
COVID-19 Coronavirus Disease 2019
CR Complete Remission
CYP Cytochrome P450
DDR DNA Damage Response
DISC Death-Inducing Signaling Complex
DNA Deoxyribonucleic Acid
DR3 Death Receptor 3
EGFR Epidermal Growth Factor Receptor
EPR Enhanced Permeability and Retention
FADD Fas-Associated Protein With Death Domain
FDA Food and Drug Administration
GDP Guanosine 5′-Diphosphate
GTP Guanosine 5′-Triphosphate
IC50 Half-Maximal Inhibitory Concentration
ID Injected Dose
ILs Interleukins
Lys Lysine
MCL-1 Myeloid Cell Leukemia 1
MDR Multidrug Resistance
MOMP Mitochondria Outer Membrane Permeabilization
MRD Minimal Residual Disease
MRE11 Meiotic Recombination 11 Homolog 1
MRI Magnetic Resonance Imaging
MRN MRE11–RAD50–NBS1
mRNA Messenger Ribonucleic Acid
MTD Maximum Tolerated Dose
NLC Nanostructured Lipid Carriers
NNI National Nanotechnology Initiative
Orn Ornithine
pCR Pathological Complete Response
PEG Polyethylene Glycol
Phe Phenylalanine
PSMA Prostate Specific Membrane Antigen
RAD50 Double Strand Break Repair Protein
RB Retinoblastoma
RES Reticuloendothelial System
SAC Spindle Assembly Checkpoint
SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2
scFv Single Chain Fragment Variable
SCLC Small Cell Lung Cancer
SGT-53 Tumor Suppressor Gene TP53/scL-p53
SLN Solid Lipid Nanoparticles
SN-38 7-Ethyl-10-Hydroxycamptothecin
SN-38G SN-38 Glucuronide
t 1/2 Elimination half-life
TfR Transferrin Receptor
TL1A TNF-Like Cytokine 1A
TNF Tumor Necrosis Factor
TOP1cc Topoisomerase I-DNA Cleaved Complexes
Trp Tryptophan
Tyr Tyrosine
UGT1A Uridine Diphosphate Glucuronosyltransferase 1A
Vd Volume of Distribution
VYXEOS Liposomal Cytarabine/Daunorubicin