Table 1.
Target | Drug | Immunotherapy Type | Use and Clinical Indication |
---|---|---|---|
CD19 | Blinatumomab [39] | BiTE | ALL |
Tisagenlecleucel [40] | CAR | ALL | |
Brexucabtagene Autoleucel [40] | CAR | ALL | |
CD20 | Rituximab [33] | Monoclonal Ab | ALL, CLL |
Ofatumumab [34] | Monoclonal Ab | CLL | |
Obinutuzumab [35] | Monoclonal Ab | CLL | |
CD22 | Epratuzumab [37] | Monoclonal Ab | ALL (orphan drug) |
Inotuzumab ozogamicin (InO) [38] | Monoclonal Ab | ALL | |
CD52 | Alemtuzumab [41] | Monoclonal Ab | CLL |