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. 2021 Oct 26;13(21):5355. doi: 10.3390/cancers13215355
CAF Cancer-associate fibroblast
CCND1 Cyclin D1
CDKN2A Cyclin-dependent kinase inhibitor 2A
CXCL1 C-X-C motif chemokine ligand 1
DFS Disease-free survival
DNA Deoxyribonucleic acid
EGF Epidermal growth factor
EGFR Epidermal growth factor receptor
EMA European medicines agency
EMT-TF EMT transcription factor
EMT Epithelial-to-mesenchymal transition
EpCAM Epithelial cell adhesion molecule
EPIC Estimating the proportion of immune and cancer cells
EZH2 Enhancer of zeste 2
FDA Food and drug administration
FHCC Fred Hutchinson cancer center
GLI1 Glioma-associated oncogene 1
GSEA Gene set enrichment analysis
HIF1α Hypoxia-induced factor 1 alpha
HNSCC Head and neck squamous cell carcinoma
HPV Human papillomavirus
IL Interleukin
ITH Intra- and intertumoral heterogeneity
Malat1 Metastasis-associated lung adenocarcinoma transcript 1
MATH Mutant allele tumor heterogeneity
MDACC MD Anderson cancer center
miRNA MicroRNA
MMP Matrix metalloproteinase
MRD Minimal residual disease
MTD Maximal tolerable dose
MYC Myc oncogene (Myelocytomatosis oncogene homolog)
NPC Nasopharyngeal carcinoma
OS Overall survival
OSCC Oral squamous cell carcinoma
P53 Tumor protein P53
PD-L1 Programmed death ligand 1
PD1 Programmed cell death protein 1
pEMT Partial EMT
PI3KCA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PRRX1 Paired-related homeobox 1
R(C)T Radio(chemo)therapy
RNA Ribonucleic acid
SCC Squamous cell carcinoma
scRNAseq Single cell RNA sequencing
SMAD Sma and Mad protein homologs
TCGA The cancer genome atlas
TGFβ Transforming growth factor beta
TGFβR Transforming growth factor beta receptor
WNT Wingless integrated
ZEB Zinc finger E-box-binding homeobox protein