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Blending strategy for development of a versatile silk-based drug delivery system. Silk proteins are blended depending on demand before the material (e.g., spheres) formation. (A). Blending two types of silk (S1 and S2) to obtain spheres of distinct properties. (B). Blending silk proteins of two (or more) distinct functionalization to obtain multifunctional material. (C). Blending silk proteins at various ratios to control material’s avidity to cells, drugs, and others molecules.
