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. 2021 Oct 30;13(21):5466. doi: 10.3390/cancers13215466

Table 1.

Clinico-pathological characteristics of 315 pancreatic cancer patients stratified by I-score (high vs. low).

Characteristic Total I-Score p-Value
(n = 315) Low (n = 239) High (n = 76)
Age Mean ± SD 65.4 ± 9.7 65.8 ± 9.6 64.1 ± 10 0.1862
Sex
Male 181 (57.5%) 136 (75.1%) 45 (24.9%) 0.7231
Female 134 (42.5%) 103 (76.9%) 31 (23.1%)
Status
Resectable 110 (34.9%) 104 (94.5%) 6 (5.5%) <0.0001
Locally advanced 78 (24.8%) 74 (94.9%) 4 (5.1%)
Metastatic 127 (40.3%) 61 (48.0%) 66 (52.0%)
Pancreatic tumor location
Body or tail 164 (52.1%) 108 (65.9%) 56 (34.1%) <0.0001
Head or neck 151 (47.9%) 131 (86.8%) 20 (13.2%)
CA19-9, U/mL a
≤37 106 (34.1%) 95 (98.6%) 11 (10.4%) <0.0001
>37 205 (65.9%) 141 (68.8%) 64 (31.2%)
CEA, U/mL b
≤5 152 (53.3%) 138 (90.8%) 14 (9.2%) <0.0001
>5 133 (46.7%) 77 (57.9%) 56 (42.1%)
ECOG
0 + 1 309 (98.1%) 234 (75.7%) 75 (24.3%) >0.9999
2 + 3 6 (1.9%) 5 (83.3%) 1 (16.7%)

Missing value a = 4, b = 30. Standard deviation, SD; carbohydrate antigen 19-9, CA19-9; carcinoembryonic antigen, CEA; Eastern Cooperative Oncology Group, ECOG.