Table 3.
Genomic coordinates of GISTIC regions containing known pancreatic cancer related genes.
| Amp/Del | GISTIC Amp/Del Region | Curated Pancreatic Cancer-Related Gene | ||||||
|---|---|---|---|---|---|---|---|---|
| Chr | Start | End | Chr | Start | End | Gene | Type | |
| Amp | chr3 | 174,000,002 | 198,022,430 | chr3 | 187,439,164 | 187,463,513 | BCL6 | OCG |
| chr3 | 178,866,310 | 178,952,497 | PIK3CA | OCG | ||||
| chr8 | 125,000,002 | 146,364,022 | chr8 | 128,748,314 | 128,753,680 | MYC | OCG | |
| chr8 | 141,668,480 | 142,011,412 | PTK2 | PPA | ||||
| chr12 | 24,000,002 | 27,000,000 | chr12 | 25,358,179 | 25,403,854 | KRAS | OCG | |
| chr19 | 31,000,002 | 59,128,983 | chr19 | 45,251,977 | 45,263,301 | BCL3 | OCG | |
| chr19 | 45,281,125 | 45,303,903 | CBLC | OCG | ||||
| chr19 | 40,736,223 | 40,791,302 | AKT2 | OCG | ||||
| chr19 | 39,390,339 | 39,399,534 | NFKBIB | PPA | ||||
| chr19 | 39,078,280 | 39,108,643 | MAP4K1 | PPA | ||||
| chr19 | 39,876,269 | 39,881,835 | PAF1 | PPA | ||||
| chr19 | 38,924,339 | 39,078,204 | RYR1 | PPA | ||||
| Del | chr9 | 1 | 27,000,000 | chr9 | 4,985,244 | 5,128,183 | JAK2 | OCG |
| chr9 | 21,802,634 | 21,865,969 | MTAP | TSG | ||||
| chr9 | 21,967,750 | 21,994,490 | CDKN2A | TSG | ||||
| chr9 | 22,002,901 | 22,009,312 | CDKN2B | TSG | ||||
| chr9 | 8,314,245 | 10,612,723 | PTPRD | TSG | ||||
Amplification, Amp; deletion, Del; Oncogene, OCG; tumor suppressor gene, TSG; poor prognosis with amplification, PPA.