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. 2021 Oct 29;13(21):5420. doi: 10.3390/cancers13215420

Figure 1.

Figure 1

Hemodynamic Tissue Signature (HTS) method, including the four phases: 1. Preprocessing of morphological MRIs (T1, T1c, T2, and Flair); 2. Glioblastoma tissue segmentation; 3. DSC perfusion quantification; and 4. HTS vascular habitats. HAT: High Angiogenic Tumor, LAT: Low Angiogenic Tumor, IPE: Infiltrated Peripheral Edema, and VPE: Vasogenic Peripheral Edema.