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. 2021 Oct 23;13(21):5322. doi: 10.3390/cancers13215322

Figure 2.

Figure 2

The expression profile of miR-33a, which was modulated by mimic and anti-miR transfections, in 17-β-Estradiol (E2) or Fulvestrant (FUL) treated MCF-7 and MDA-MB-231 cells. The relative miR-33a expression in 17-β-Estradiol (E2) and Fulvestrant (FUL) treated MCF-7 (a) and MDA-MB-231 (b) cells were detected by the qRT-PCR assay. Columns represent the mean ± Std.dev of three independent experiments with two repeats (* p = 0.0491 in MCF-7 cells, * p = 0.0381 in MDA-MB-231, by one-way ANOVA, Dunnett’s multiple comparison test). The mimic and anti-miR transfections changed the expression of miR-33a in MCF-7 cells (c) and in MDA-MB-231 cells (d). Columns represent the mean ± Std.dev of three independent experiments with two repeats (**** p < 0.0001 by two-way ANOVA, Tukey’s multiple comparison test).