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L3SMI is a sex-specific preoperative predictor for overall survival in patients undergoing surgery for CCA. Using the median (45.313 cm2/m2) for L3SMI of the total study cohort as a cut-off for overall survival in male (A) and female (C) subgroups, only in male patients could a significant difference in overall survival be identified. After using sex-specific cut-off values differences were seen in male patients (48.48 cm2/m2) only (B,D). n.s. = not significant.
