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The isoforms of O-GlcNAc transferase (OGT) and the role of O-GlcNAcylation. OGT has three isoforms: nucleocytoplasmic OGT (ncOGT), mitochondrial (mOGT), and short OGT (sOGT). O-GlcNAcylation is involved in transcriptional regulation, post-translational modification, epigenetic alteration, cell signal transduction, and hormone and cytokine secretion.
