Table 4.
Stage | UICC/WHO 2003 | ENSAT 2008 | UICC 2020 (since 2010) | AJCC, 8th Edition |
---|---|---|---|---|
I | T1, N0, M0 | T1, N0, M0 | T1, N0, M0 | T1, N0, M0 |
II | T2, N0, M0 | T2, N0, M0 | T2, N0, M0 | T2, N0, M0 |
III | T1–2, N1, M0 T3, N0, M0 |
T1–2, N1, M0 T3–4, N0–1, M0 |
T1–2, N1, M0 T3–4, N0–1, M0 |
T3, N0, M0 T1/2, N1, M0 T4, N0, M0 T3/4, N1, M0 |
IV | T1–4, N0–1, M1 T3, N1, M0 T4, N0–1, M0 |
T1–4, N0–1, M1 | T1–4, N0–1, M1 | T1–4, N0–1, M1 |
Definition of tumor stages: T1—tumor ≤ 5 cm; T2—tumor > 5 cm; T3—tumor infiltration in the surrounding tissue; T4—tumor invasion in the adjacent organs (ENSAT: also venous tumor thrombus in the vena cava/renal vein); N0—no positive lymph nodes; N1—positive lymph node(s); M0—no distant metastasis; M1—presence of distant metastasis.