Figure 3.
The inhibition of NETs improves the response to anti-PD-1 therapy, which is associated with a lack of CD8+ T cell infiltration. (A,B) Percentages of CD8+ T cells within the tumors from mice undergoing different treatments; n = 4 mice/group. (C,D) Percentages of CD4+ T cells within the tumors from mice undergoing different treatments; n = 4 mice/group. The graphs show the means ± SD (B,D). ANOVA was performed with adjustment for multiple comparisons for (B,D). Note: * p < 0.05, ** p < 0.01, *** p < 0.001; NS: not significant. All statistical tests used in this figure were two-sided and p < 0.05 was considered statistically significant.
