Table 1.
The recruitment strategies, numbers of subjects approached, numbers of respondents and the percentage of respondents randomised in major European lung cancer screening trials.
| Lung Cancer Screening Trial | Recruitment Period | Number of Subjects Approached | Number of Subjects That Responded | Approach Response Rate | Number of Eligible Subjects That Consented | % of Respondents Randomised | Method of Recruitment |
|---|---|---|---|---|---|---|---|
| NELSON [6] | 2003–2006 | 606,409 | 150,920 | 24.9% | 15,822 | 10.5% | Direct mail |
| ITALUNG [22] | 2004–2006 | 71,232 | 17,055 | 23.9% | 3206 | 18.8% | Direct mail |
| LUSI [23] | 2007–2011 | 292,440 | 95,797 | 32.8% | 4052 | 4.2% | Direct mail and mass media |
| NLST [18] | 2002–2004 | n/a | 53,454 | n/a | 52,486 | n/a | Direct mail, mass media and outreach |
| UKLS [8] | 2011–2014 | 247,354 | 98,746 | 39.9% | 4061 | 4.1% | Direct mail |
| LSUT [24] | 2015–2017 | 2012 | 1058 | 52.6% | 770 | 72.8% | Direct mail |
| LHC Manchester [25] | 2016–2018 | 16,402 | 2827 | 17.2% | 1384 | 49.0% | Searched GP records to send direct mail invitations |
| LHC Liverpool [26] | 2016–2018 | 11,526 | 4566 | 39.6% | 1318 | 28.9% | Searched GP records to send direct mail invitations |
| ECLS [9] | 2013–2016 | 77,077 | 18,657 | 24.2% | 12,209 | 65.4% | Searched GP records to send direct mail invitations, mass media and outreach |