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. 2021 Oct 29;13(21):5451. doi: 10.3390/cancers13215451

Figure 1.

Figure 1

A domain scheme of the LUBAC complex. The LUBAC complex includes three proteins, RNF31, SHARPIN and HOIL1, with RNF31 being the core. PUB: PNGase/UBA or UBX-containing proteins; NZF: Npl4-type zinc finger domain; UBA: ubiquitin-associated domain; IBR: in-between RING domain; UBL: ubiquitin-like domain.