Table 3.
CRS history of APVO436-treated R/R AML patients with favorable responses.
| Patient ID | Cohort | CRS | Best Overall Response |
|---|---|---|---|
| 214-0002 | 1 | +(Grade 3) | SD |
| 214-0008 | 5 | - | SD |
| 215-0004 | 6A | +(Grade 1) | SD |
| 212-0005 | 6A | +(Grade 1) | PR CR |
| 213-0009 | 6B | - | PR CR |
| 214-0011 | 7 | +(Grade 2) | SD + PBBC-C+ >50%BMB reduction |
| 213-0012 | 10 | - | SD |
| 218-0004 | 10 | - | SD/RES |
PBBC-C: Clearance of peripheral blood blast count; BMB: bone marrow blast count; SD: stable disease; RES: resistant disease; PR: partial remission; CR: complete remission.