Table 1.

Viral load (average viral copies for ml) at day 0 and at day 7. The data for 5 and 10 min of sampling, from the residual liquid in the nebulizer, and for the initial dilution prior to testing are reported. Cytopathic effects (CPE) and p-value from the results of Mann–Whitney test (MW) are also shown. ns = not significant statistical analysis.

	105 PFU/mL				104 PFU/mL				103 PFU/mL
	Day 0	Day 7	CPE	MW	Day 0	Day 7	CPE	MW	Day 0	Day 7	CPE	MW
10′ sampling	9.1 × 107	6.2 × 109	+	0.0001	4.6 × 106	1.2 × 109	-	0.02	9.9 × 105	9.7 × 105	-	ns
5′ sampling	4.2 × 107	3.7 × 109	+	0.001	2.4 × 106	2.3 × 108	-	0.02	5.4 × 105	9.9 × 105	-	ns
nebulizer after aerosolization	2.1 × 109	1.6 × 1010	+	0.03	4.1 × 108	1.4 × 1010	+	0.03	3.4 × 107	8.2 × 109	+	0.03
Initial prior to testing	5.1 × 109	9.1 × 109	+	ns	4.2 × 108	1.3 × 1010	+	ns	4.6 × 107	5.4 × 109	+	ns