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The kynurenine pathway. IDO, indoleamine 2,3-dioxygenase; TDO, tryptophan 2,3-dioxygense; AFMID, arylformamidase; KAT-2, aminoadipate aminotransferase; KAT-3, kynurenine aminotransferase 3; KYNU, kynureninase; KMO, kynurenine 3-monooxygenase; HAAO, 3-hydroxyanthranilate 3,4-dioxygenase; ACMSD, aminocarboxymuconate semialdehyde decarboxylase; QPRT, quinolinate phosphoribosyltransferase.
