CCHS |
Congenital Central Hypoventilation Syndrome |
ChIP-seq |
Chromatin Immunoprecipitation Sequencing |
E10.5, E11.5 |
Embryonic Developmental Mouse Timeline Expressed in Days |
EMT |
Epithelial-to-Mesenchymal Transition |
ESCs |
Embryonic Stem Cells |
FS |
Frameshift |
HD |
Homeodomain |
HSCR |
Hirschsprung Disease |
iPSC/s |
Induced Pluripotent Stem Cell/s |
miRNA |
microRNA |
MRX34 |
Liposomal Formulation of miR-34a Mimics |
MS |
Missense |
NC |
Neural Crest |
NCCs |
Neural Crest Cells |
NICDs |
Notch Intracellular Domains |
NSCs |
Neural Stem Cells |
RNAi |
RNA Interference |
scRNA-seq |
Single-Cell RNA Sequencing |
shRNA |
Short Hairpin RNA |
siRNA |
Small Interference RNA |
SNPs |
Single Nucleotide Polymorphisms |
SNS |
Sympathetic Nervous System |
UTR |
Untraslated Region |
AGO2 |
Argonaute RISC Catalytic Component 2 |
AKT |
Serine/Threonine Kinase |
ALK/ALK |
Anaplastic Lymphoma Kinase (receptor tyrosine kinase) |
ALKAL2 |
ALK Additionally, LTK Ligand 2 |
AP-1 |
Activator Protein-1 |
Ascl1/ASCL1 |
Achaete-Scute Family bHLH Transcription Factor 1 |
BANCR |
BRAF-activated non-protein coding RNA |
bHLH |
Basic Helix-Loop-Helix |
BLIMP1 |
B-Lymphocyte-Induced Maturation Protein 1 |
BMI1 |
BMI1 Polycomb Ring Finger Proto-Oncogene |
BMP |
Bone Morphogenetic Protein |
CCL2 |
C-C Motif Chemokine Ligand 2 |
CCNA2 |
Cyclin A2 |
CCNG2 |
Cyclin G2 |
CDK4 |
Cyclin dependent kinase 7 |
CDKL5 |
Cyclin Dependent Kinase Like 5 |
CDKN1A |
Cyclin Dependent Kinase Inhibitor 1A |
CHK1 |
Checkpoint Kinase 1 |
c-Myc/c-Myc |
c-MYC proto-oncogene; homolog of v-myc avian myelocytomatosis viral related oncogene (hematopoietic cancer-derived), bHLH Transcription Factor |
CRMP1 |
Collapsin Response Mediator Protein 1 |
c-SRC |
SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase |
CYP26A1 |
Cytochrome P450 Family 26 Subfamily A Member 1 |
DBH |
Dopamine Beta-hydroxylase |
DDC |
DCC Netrin 1 Receptor |
DKC1 |
Dyskerin Pseudouridine Synthase 1 |
DKK1 |
Dickkopf WNT Signaling Pathway Inhibitor 1 |
DLL3 |
Delta Like Canonical Notch Ligand 3 |
E2F8 |
E2F Transcription Factor 8 |
EFNB3 |
Ephrin-B3 |
EGFR |
Epidermal Growth Factor Receptor |
ERK or MAPK1 |
Mitogen-Activated Protein Kinase 1 |
ERK3 or MAPK12 |
Mitogen-Activated Protein Kinase 12 |
ERK5 or MAPK7 |
Mitogen-Activated Protein Kinase 7 |
FAK |
Focal Adhesion Kinase |
FGF |
Fibroblast Growth Factor |
FOS |
Fos Proto-Oncogene |
Foxd3 |
Forkhead Box D3 |
FZD7 |
Frizzled Class Receptor 7 |
GAP43 |
Growth Associated Protein 43 |
Gata2/GATA2 |
GATA Binding Protein 2 |
Gata3/GATA3 |
GATA Binding Protein 3 |
Hand2/HAND2 |
Heart and Neural Crest Derivatives Expressed 2 |
HDAC1 |
Histone Deacetylase 1 |
HES |
Hairy and Enhancer of Split |
HMGA2 |
High Mobility Group AT-Hook 2 |
HRAS |
Harvey Rat Sarcoma Virus Proto-Oncogene |
HuC |
RNA-Binding Protein HuC |
HuD |
RNA-Binding Protein HuD |
ID2 |
Inhibitor of DNA Binding 2 |
IL-6 |
Interleukin 6 |
INHBA |
Inhibitor of DNA Binding 2 |
ISL1 |
Islet LIM Homeobox 1 |
JUN |
Jun Proto-Oncogene |
Klf2, KLF2 |
Kruppel Like Factor 2 |
Klf4, KLF4 |
Kruppel Like Factor 4 |
KRAS |
Kirsten Rat Sarcoma Virus |
Lif |
LIF Interleukin 6 Family Cytokine |
LIN28A |
Lin-28 Homolog A |
Lin28b/LIN28B |
Lin-28 Homolog B |
LMO1 |
LIM Domain Only 1 |
LMO4 |
LIM Domain Only 4 |
MAML3 |
Mastermind Like Transcriptional Coactivator 3 |
MAPK |
Mitogen-Activated Protein Kinase |
MAX |
MYC Associated Factor X |
MCM |
Minichromosome Maintenance Protein Complex |
MCP-1 |
Monocyte Chemoattractant Protein-1 |
MDM2 |
Murine Double Minute 2 |
MEIS |
Meis Homeobox |
MEK3 or MAPK3 |
Mitogen-Activated Protein Kinase 3 |
MEK5 or MAPK5 |
Mitogen-Activated Protein Kinase 5 |
MET |
MET Proto-Oncogene, Receptor Tyrosine Kinase |
Miz-1/MIZ-1 |
Zinc Finger MIZ-Type Containing 1 |
MKP3 |
Mitogen-Activated Protein Kinase Phosphatase 3 |
MSX1 |
Msh Homeobox 1 |
MYBL2 |
MYB Proto-Oncogene Like 2 |
MYC |
MYC Transcription factor family, bHLH |
Myc-ERT |
Tamoxifen-Inducible Myc |
MYCL |
MYCL Proto-Oncogene; homolog of v-myc avian myelocytomatosis viral related oncogene (lung cancer-derived), bHLH Transcription Factor |
Mycn/MYCN |
MYCN Proto-Oncogene; homolog of v-myc avian myelocytomatosis viral related oncogene (neuroblastoma-derived), bHLH Transcription Factor |
Nanog |
Nanog Homeobox |
NeuroD1 |
Neuronal Differentiation 1 |
NFKB |
Nuclear Factor Kappa-B |
Notch/NOTCH |
Notch Receptor 1 |
NTRK2 |
Neurotrophic Receptor Tyrosine Kinase 2 |
Oct3/4 |
Octamer-Binding Transcription Factor 3/4 |
p21 |
alias Cyclin Dependent Kinase Inhibitor 1A (CDKN1A) |
P75NTR |
p75 Neurotrophin Receptor |
PC12 |
Pheochromocytoma Cells 12 |
PD-L1 |
Programmed Cell Death 1 Ligand 1 |
Phox2a/PHOX2A |
Paired Like Homeobox 2A |
Phox2b/PHOX2B |
Paired Like Homeobox 2B |
PI3K |
Phosphatidylinositol 3-Kinase |
PRRX1 |
Paired Related Homeobox 1 |
PUMA |
p53 Upregulated Modulator of Apoptosis |
RAN |
RAN, Member RAS Oncogene Family |
RARB |
Retinoic Acid Receptor Beta |
RAS |
Rat Sarcoma Oncogene |
RET |
Rearranged During Transfection |
RUNX1 |
RUNX Family Transcription Factor 1 |
SKP2 |
S-Phase Kinase Associated Protein 2 |
SNAI1 |
Snail Family Transcriptional Repressor 1 |
Snail2/SNAI2 |
Snail Family Transcriptional Repressor 2 |
Sox2 |
SRY-Box Transcription Factor 2 |
Sox 9 |
SRY-Box Transcription Factor 9 |
Sox10/SOX10 |
SRY-Box Transcription Factor 10 |
SP1 |
Specificity Protein 1 |
SSEA-1 |
Stage-Specific Embryonic Antigen 1 |
TBX2 |
T-box Transcription Factor 2 |
TG2 |
Tissue Transglutaminase 2 |
TGF-β1 (TGFB1) |
Transforming Growth Factor Beta 1 |
TH |
Tyrosine Hydroxylase |
TIMP2 |
Tissue Inhibitor of Metalloproteinases 2 |
TP53 |
Tumor Protein P53 |
TP53INP1 |
Tumor Protein P53 Inducible Nuclear Protein 1 |
Tra2β |
Transformer 2 Beta Homolog |
Trk |
Tropomyosin Receptor Kinase |
TrkB/TRKB |
Tropomyosin-Related Kinase B |
TWIST1 |
Twist Family bHLH Transcription Factor 1 |
VEGF |
Vascular Endothelial Growth Factor |
Wnt/WNT |
Wingless-Type MMTV Integration Site Family |
ZCCHC11 |
Zinc Finger CCHC Domain-Containing Protein 11 |
ZEB1 |
Zinc finger E-box Binding homeobox 1 |
ZNF143 |
Zinc Finger Protein 143 |