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. 2021 Oct 31;13(21):5484. doi: 10.3390/cancers13215484

Figure 1.

Figure 1

Role of FAs deriving from lipolysis and lipophagy. Besides the energetic role that FAs play when oxidised into mitochondria, they are useful in membrane building block biosynthesis. This function regulates the fluidity of the plasma membrane, which increases during the metastatic process. Moreover, FAs can act as second messengers, activating transcriptional factors and transducing the signal into the nucleus.