TABLE 2.
Positive PCR results for febrile neutropenic patients with lung infiltrates and proven (by histology and/or by culture) or probable (by HR-CT findings) invasive aspergillosisa
| Patient no. (age [yr]) | Diagnosis | Diagnostic tests | Sample with positive PCR findings | Outcome |
|---|---|---|---|---|
| 1 (54) | AML | HR-CT | B | Died (IA) |
| 2 (36) | AML | HR-CT, histology (chest surgery) | B | Died (IA) (relapse after BMT) |
| 3 (62) | ALL | Culture | B, BAL | Died (IA) |
| 4 (60) | AML | Histology (autopsy) | BAL | Died (IA) |
| 5 (61) | AML | HR-CT | B | Died (leukemia) |
| 6 (75) | AML | HR-CT | B | Died (leukemia) |
| 7 (75) | HD | HR-CT | B, BAL | Alive |
| 8 (42) | AML | HR-CT, histology (liver puncture) | B | Alive |
| 9 (50) | AML | HR-CT, histology (chest surgery), antigen assay | B | Alive |
| 10 (38) | AML | HR-CT, antigen assay | B, BAL | Died (leukemia) |
| 11 (30) | AML | HR-CT | B | Died (leukemia) |
| 12 (32) | SAA (post BMT) | HR-CT, culture, antigen assay | B, BAL | Alive |
| 13 (25) | ALL | Chest X ray | B | Died (IA) |
| 14 (67) | AML | HR-CT, histology (liver puncture) | B, BAL | Died (IA) |
| 15 (61) | AML | Histology (autopsy) | B, BAL | Died (leukemia) |
| 16 (64) | AML | HR-CT | BAL | Died (leukemia) |
| 17 (56) | AML | HR-CT | B | Died (leukemia) |
| 18 (69) | ALL | HR-CT | B | Died (leukemia) |
| 19 (20) | ALL | HR-CT | B | Died (BMT) |
| 20 (39) | CML-BC | HR-CT | B | Died (leukemia) |
| 21 (62) | CML-BC | HR-CT, culture | B, BAL | Died (leukemia) |
| 22 (56) | AML | HR-CT | B | Died (leukemia) |
a
Abbreviations: AML, acute myeloid leukemia; IA, invasive aspergillosis; HD, Hodgkin's disease; SAA, severe aplastic anemia; BMT, bone marrow transplantation; ALL, acute lymphoblastic leukemia; B, blood; CML-BC, chronic myelogenous leukemia blast crisis.