Table 2.
Differentially expressed P. aeruginosa PAO1 genes at 5 min post-infection that have medium-specific expression
Gene | Annotation | COG category | Functional Category | LB t = 5 min |
MCCM t = 5 min |
LB t = 10 min |
MCCM t = 10 min |
LB t = 15 min |
MCCM t = 15 min |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Log2Fold | padj | Log2Fold | padj | Log2Fold | padj | Log2Fold | padj | Log2Fold | padj | Log2Fold | padj | ||||
PA3584 | glpD | [C] Energy production and conversion | Metabolism | −1.3 | 1.00E-03 | 2.5 | 1.32E-06 | −1.03 | 2.28E-02 | 1.51 | 9.88E-02 | −0.27 | 8.06E-01 | 0.41 | 8.81E-01 |
PA2204 | Probable binding protein component of ABC transporter | [E] Amino acid transport and metabolism | −2 | 9.32E-05 | 2.9 | 3.70E-15 | −1.06 | 9.15E-02 | 1.49 | 6.39E-02 | −0.37 | 8.06E-01 | 0.78 | 6.26E-01 | |
PA5304 | dadA | [E] Amino acid transport and metabolism | −0.9 | 2.20E-02 | 2.8 | 7.28E-10 | 0.10 | 8.54E-01 | 3.82 | 4.45E-20 | 0.67 | 2.29E-01 | 2.69 | 1.21E-08 | |
PA5429 | aspA | [E] Amino acid transport and metabolism | −1.2 | 4.68E-06 | 1.9 | 5.00E-03 | −0.67 | 2.88E-02 | 3.02 | 2.91E-06 | −0.53 | 3.63E-01 | 2.75 | 5.32E-05 | |
PA0975 | Hypothetical protein | [H] Coenzyme transport and metabolism | −0.8 | 4.00E-03 | 1.1 | 1.60E-02 | −0.43 | 2.36E-01 | 0.23 | 8.77E-01 | −0.16 | 9.08E-01 | 0.52 | 6.60E-01 | |
PA5118 | thiI | [H] Coenzyme transport and metabolism | −0.9 | 1.00E-03 | 1.1 | 3.30E-02 | −1.05 | 5.70E-05 | 1.32 | 3.06E-02 | −0.88 | 5.46E-02 | 1.28 | 4.40E-02 | |
PA2557 | Probable AMP-binding enzyme | [I] Lipid transport and metabolism | 1.2 | 3.50E-02 | −1 | 1.40E-02 | 1.48 | 7.41E-03 | −2.14 | 1.67E-04 | 1.27 | 2.83E-01 | −3.29 | 4.52E-08 | |
PA2071 | Elongation factor G | [J] Translation, ribosomal structure and biogenesis | Information storage and processing | 1.1 | 1.00E-03 | −1.2 | 3.00E-03 | 0.74 | 1.25E-01 | −1.15 | 4.50E-02 | 0.41 | 7.65E-01 | −1.61 | 3.12E-02 |
PA0483 | Probable acetyltransferase | [K] Transcription | 1.1 | 4.10E-02 | −1.6 | 2.00E-03 | 0.37 | 6.07E-01 | −2.20 | 2.25E-03 | 0.36 | 8.39E-01 | −3.65 | 2.14E-03 | |
PA0528 | Transcriptional repressor | [K] Transcription | −1.2 | 6.00E-03 | 1.8 | 4.70E-02 | −1.08 | 1.98E-02 | 1.48 | 4.27E-01 | −0.74 | 4.47E-01 | −0.45 | 9.50E-01 | |
PA5374 | betI | [K] Transcription | −1.3 | 1.00E-03 | 4.5 | 2.09E-16 | −1.63 | 5.78E-05 | 4.55 | 8.04E-16 | −1.34 | 2.25E-02 | 4.35 | 3.08E-07 | |
PA3642 | Ribonuclease HII, rnhB | [L] Replication, recombination and repair | −0.8 | 3.20E-02 | 1 | 2.70E-02 | −1.64 | 1.64E-05 | 0.45 | 6.90E-01 | −1.30 | 1.09E-02 | 0.14 | 9.48E-01 | |
PA5302 | dadX | [M] Cell wall/membrane/envelope biogenesis | Cellular processes and signalling | −1 | 9.00E-03 | 2.9 | 4.67E-07 | −0.18 | 7.59E-01 | 3.65 | 6.07E-16 | 0.51 | 5.36E-01 | 2.88 | 3.62E-08 |
PA1181 | Hypothetical protein, sensor protein | [T] Signal transduction mechanisms | Cellular processes and signalling | −0.9 | 2.00E-03 | 1.1 | 9.00E-03 | −0.71 | 5.00E-02 | 1.21 | 2.72E-02 | 0.02 | 9.89E-01 | 0.62 | 5.73E-01 |