Figure 2.

Thiobarbituric acid reactive substances (TBARS) content expressed as the level of malondialdehyde (MDA), a product of membrane lipid peroxidation (A), the level of total SH groups (B), protein SH groups (C), and non-protein SH groups (D) in brain homogenate obtained from the control, experimental autoimmune encephalomyelitis (EAE) rats and memantine-treated EAE rats in different phases of the disease. The results are the means from n = 4 animals and are expressed as percentages of the control. * p < 0.05, ** p < 0.01, *** p < 0.001 significantly different vs. control rats. ^# p < 0.05, ^### p < 0.01 significantly different vs. untreated EAE rats (one-way ANOVA with post hoc Bonferroni’s test).