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. 2021 Oct 20;22(21):11324. doi: 10.3390/ijms222111324

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Co-expression network between lncRNAs and mRNAs in each module. (A) Module 1 shows genes enriched in pathways associated with cell death, apoptosis, and necrosis. (B) Module 2 shows genes predicted to activate pathways involved in angiogenesis and vascular development in the cardiovascular system and proliferation of white blood cells and immune cells. Yellow nodes represent lncRNAs with the highest module membership and putative hub genes; Red nodes represent (annotated) lncRNAs; Green node (Module 1) represents the ischemia associated novel lncRNA; Purple nodes represent mRNAs.