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Genes mutated in inherited thrombocytopenia and encoding for up- and down-stream molecules of Rho-GTPase pathways
| Macrothrombocytopenia | Microthrombocytopenia | |
|---|---|---|
| RHOA effectors | MYH9, DIAPH1 | |
| CDC42 effectors | WASP, ADAP, ARPC1B | |
| Cytoskeleton components | FLNA, ACTN1, TUBB1, TPM4 | |
| Receptor and signalling molecules | GP1BA, GPI1BB, GP9, ITGA2, ITGB3, SRC, TRPM7 | PTPRJ |
