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. 2021 Nov 8;10(1):2001159. doi: 10.1080/2162402X.2021.2001159

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© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Application of PancVax gel following incomplete tumor resection. (a) Flow cytometry was performed on the digested tumor remnant and surrounding tissue on the indicated postoperative day following incomplete resection and either PancVax gel or control gel implantation. Immune cell breakdown by percentage of CD45⁺ cells is shown in sunburst plots. (b) Neutrophil and MDSC percentages in the tumor remnant are shown over time. (c) NK cell subpopulations are shown in the tumor remnant over time. (d) CD8⁺ T cell activation markers are shown in the draining lymph node (right inguinal) over time postoperatively. (e) NK cell subpopulations are shown in the draining lymph node over time postoperatively. Error bars indicate standard error of the mean. * P < .05, ** P < .01, *** P < .001. Sunburst plots display M1 macrophages in yellow, M2 macrophages in light blue, MDSCs in gray, Neutrophils in Orange, NK cells in royal blue, CD4⁺ T cells in green and CD8⁺ T cells in dark blue