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. 2021 Nov 8;10(1):2001159. doi: 10.1080/2162402X.2021.2001159

Figure 4.

Figure 4.

Immunologic changes at two weeks following incomplete tumor resection and PancVax gel application. (a) Flow cytometry was performed on the digested tumor remnant and surrounding tissue on postoperative day 14 following incomplete resection and either PancVax gel or control gel implantation. Immune cell breakdown by percentage of CD45+ cells is shown in sunburst plots and (b) selected dot plots. (c) Immune cell breakdown is shown in the draining lymph node (right inguinal) at two weeks following incomplete tumor resection and PancVax gel or control gel implantation in sunburst and (d) selected dot plots. (e) Immune cell breakdown is shown in the spleen at two weeks following incomplete tumor resection and PancVax gel or control gel implantation in sunburst and (f) selected dot plots. Error bars indicate standard error of the mean. * P < .05, ** P < .01, *** P < .001. MFI, mean fluorescent intensity. Sunburst plots display M1 macrophages in yellow, M2 macrophages in light blue, MDSCs in gray, neutrophils in Orange, NK cells in royal blue, CD4+ T cells in dark blue, CD8+ T cells in brown and B cells in green