Table 3.
Spearman’s correlation between serum VISTA levels and immune inflammation mediators, in cats with HER2-positive, or triple-negative mammary carcinomas.
| Serum Immune Checkpoint Proteins and Cytokines Correlation | ||||||
|---|---|---|---|---|---|---|
| HER2-positive | PD-1 | PD-L1 | CTLA-4 | LAG-3 | IL-6 | TNF-α |
| VISTA | 0.0479 * | 0.2763 | 0.1206 | 0.3088 | 0.5061 | 0.0552 |
| Triple-negative | PD-1 | PD-L1 | CTLA-4 | LAG-3 | IL-6 | TNF-α |
| VISTA | 0.0005 *** | 0.0010 ** | 0.0083 ** | 0.0158 * | 0.0102 * | 0.0083 ** |
* indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001.