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. 2021 Nov 5;13(21):5548. doi: 10.3390/cancers13215548

Figure 1.

Figure 1

ESMO Clinical Practice Guideline update: Systemic first-line treatment of clear cell renal cell carcinoma (ccRCC) [14]. ccRCC, clear cell renal cell cancer; EMA, European Medicines Agency; ESMO-MCBS, European Society for Medical Oncology-Magnitude of Clinical Benefit Scale; FDA, Food and Drug Administration; IMDC, International Metastatic RCC Database Consortium; MCBS, ESMO-Magnitude of Clinical Scale; VEGFR, vascular endothelial growth factor receptor. a ESMO-MCBS v1.1 score for new therapy/indication approved by the EMA or FDA. The score has been calculated by the ESMO-MCBS Working Group and validated by the ESMO Guidelines Committee; b FDA approved; not currently EMA approved.