Table 2.

Univariate and multivariate analyses of progression-free survival of patients in YTMA454 based on expression of TIL and CAF markers. Abbreviations: HR, hazard ratio; CI, confidence interval.

Protein	Univariate Analysis		Multivariate Analysis per Variable		Multivariate Analysis CD4, CD8, Thy-1, and FAP
High/Low	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
CD4	0.68 (0.48–0.96)	0.027	0.66 (0.46–0.96)	0.027	0.95 (0.63–1.44)	0.81
CD8	0.54 (0.38–0.76)	0.0003	0.47 (0.32–0.68)	<0.0001	0.52 (0.34–0.80)	0.0028
CD20	0.84 (0.59–1.18)	0.31	0.81 (0.57–1.16)	0.26
Thy-1	0.66 (0.47–0.94)	0.02	0.65 (0.45–0.95)	0.025	0.70 (0.47–1.03)	0.69
FAP	1.66 (1.17–2.36)	0.0039	1.62 (1.13–2.33)	0.0088	1.49 (1.03–2.17)	0.037
SMA	1.25 (0.88–1.77)	0.21	1.27 (0.89–1.82)	0.19