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. 2021 Oct 28;9:757822. doi: 10.3389/fped.2021.757822

Table 4.

The table shows the daily p-SAPS II evaluation compared to the admission PIM 3 of the patients still in the study at the given timepoint.

Day N AUROC p-SAPS II (95% CI, p) AUROC PIM 3(95% CI, p) Difference (p) Goodness of fit p-SAPS II (p) Observed/expected (Ratio)
2 235 0.88 (0.83–0.93, p < 0.001) 0.716 (0.515–0.0917, p = 0.012) 0.164 (0.095) 13.42 (0.004) 12/32.5 (0.369)
3 234 0.86 (0.78–0.94, p < 0.001 0.704 (0.49–0.92, p = 0.023) 0.156 (0.15) 32.92 (<0.001) 11/52.15 (0.211)
7 129 0.895 (0.82–0.97, p < 0.001) 0.729 (0.51–0.95, p = 0.114) 0.165 (0.168) 8.74 (0.068) 9/21.95 (0.41)
14 51 0.857 (0.75–0.97, p = 0.002) 0.698 (0.45–0.94, p = 0.125) 0.159 (0.168) 3.15 (0.53) 8/14.2 (0.563)
21 27 0.889 (0.76–1, p = 0.003) 0.714 (0.44–0.99, p = 0.102) 0.175 (0.288) 1.82 (0.612) 7/6.65 (1.05)
28 17 0.96 (0.86–1, p = 0.005) 0.64 (0.29–0.99, P = 0.391) 0.32 (0.131) 0.296 (0.961) 5/4.25 (1.18)

Throughout the clinical stay, the AUROC value increases although significant differences to PIM 3 were not detected. The goodness of fit test shows improvement of fitting over time. With O/E ratios adjusting to One.