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Effects of sotrastaurin and alpelisib on immune gene expression. (a,b) Gene expression analysis of immune-related genes was performed using the Nanostring IO360 Panel. Differentially expressed genes (on-treatment versus pre-treatment, n = 7 specimens per time-point) with log2 fold change >1.5 (and raw p-value < 0.05) are graphed and listed in the table (b). There were no genes demonstrating increased expression on-treatment compared to pre-treatment.
