Table 3.
Molecular Subtypes (n, %) |
Histological Subtypes (n; %) |
T Stage Category (n) | High PD-L1 Expression (%) | Survival Status, Median ±SD (Range), in Months |
---|---|---|---|---|
LUMINAL (65; 71%) GATA3+ and/or KRT20+ |
Conventional UC (55; 84.6%) |
Ta (31); T1 (21); T2–T4 (3) |
15 (27.3%) | 49 ± 35.70 (12–125) |
Variant histology UC (10; 15.4%) (Micropapillary (4); Nested (1); Plasmacytoid (1); Other Variants (4)) |
Ta (0); T1 (6); T2–T4 (4) |
4 (40%) | 45 ± 55.36 (4–119) | |
BASAL (19; 21%) KRT5+ and/or KRT14+; GATA3−; KRT20− |
Conventional UC (8; 42.1%) |
Ta (3); T1 (3); T2–T4 (2) |
4 (50%) | 21 ± 7.34 (12–60) |
Variant histology UC (11; 57.9%) (Micropapillary (2); Nested (4); Plasmacytoid (2); Other Variants (3)) |
Ta (0), T1 (0); T2–T4 (11) |
8 (72.7%) | 9.5 ± 21.42 (2–21) | |
NULL/DOUBLE NEGATIVE (7; 8%) GATA3−; KRT20−; KRT5−; KRT14− |
Conventional UC (4; 57.1%) |
Ta (2); T1 (0); T2–T4 (2) |
2 (66.7%) | 32 ± 36.77 (6–58) |
Variant histology UC (3; 42.9%) (Nested (1); Plasmacytoid (2)) |
Ta (0); T1 (0); T2–T4 (3) |
3 (100%) | 4 ± 1.15 (2–4) |