Figure 1.

Effects of piceatannol on acute senescence. MSCs at 10 DIV were treated for 30 min with 300 μM hydrogen peroxide to induce acute senescence, which was evaluated by beta-gal assay 48 h later. Next, senescent cultures were incubated with different amounts of piceatannol for another 48 h. The upper chart (A) shows the percentage of senescent cells at the end of piceatannol treatment. The lower chart (B) reports the cell viability, as detected via CCK-8 assay, of cultures treated with piceatannol. Data are expressed in arbitrary units and shown with standard deviation (SD), n = 3. *** p < 0.001 and * p < 0.05 indicate statistical significance between the control and treated samples. CT = control samples.