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. 2021 Oct 30;22(21):11799. doi: 10.3390/ijms222111799

Table 2.

Summary of the methods presented in this review.

Method Target Super-Resolution Implementation Fixed/Live-Cell Imaging Genetically Encoded? Reference
PAINT Membranes SMLM, STED Both No [26,117]
DNA-PAINT DNA-origami, proteins SMLM, STED, SOFI Fixed No [30,34,44,118]
uPAINT Proteins SMLM Live-cell No [31]
RNA-aptamers RNA SMLM Both Partially 1 [48]
FAPs Proteins SMLM, STED, SRRF Both Partially 1 [17,61,73,77]
IRIS 2 Proteins SMLM, STED Both Both 3 [8,86,117]
KECs 4 Proteins SMLM Both Yes [21,109]
Peptide-PAINT DNA-origami, proteins SMLM Fixed No [108]

1 A combination of genetically encoded part with organic fluorogens added externally; 2 includes other methods, based on probe that transiently interacts with a specific target protein; 3 could be used either with organic dyes or fluorescent proteins; 4 and LIVE-PAINT.