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Diagram showing the contribution of tetraspanins in the influenza A virus replication cycle. Upon endocytosis, CD81 enhances viral uncoating, while CD151 facilitates vRNP nuclear export signaling. Abbreviations: IAV, influenza A virus; CD81, cluster of differentiation 81; CD151, cluster of differentiation 151; vRNP, viral ribonucleoprotein.
