Table 4.
Activities of enzymes of ETC and citrate synthase in heart mitochondria from control and hyperthyroid rats.
Enzymes | CR | HR | |
---|---|---|---|
CS, nmol/min·mg | 1386 ± 28 | 1353 ± 61 | - |
CI, nmol/min·mg | 376 ± 13 | 473 ± 17 * | 26%↑ |
CII, nmol/min·mg | 131 ± 3 | 100 ± 3 * | 31%↓ |
CI + III, nmol/min·mg | 563 ± 18 | 700 ± 25 ** | 24%↑ |
CII + III, nmol/min·mg | 644 ± 30 | 488 ± 340 ** | 32%↓ |
CIII, nmol/min·mg | 2481 ± 141 | 3170 ± 139 ** | 28%↑ |
CIV, nmol/min·mg | 2616 ± 234 | 3459 ± 188 ** | 32%↑ |
CV, nmol/min·mg | 3068 ± 105 | 2958 ± 116 | - |
* p < 0.05, ** p < 0.02, the difference is statistically significant (n = 15–20 in each group). CR—control, HR—hyperthyroidism. Changes induced by thyroxine: ↑: increase, ↓: decrease, -: no change.