Table 6.

Stability study results of the optimized gel (BT-NPopG) at per ICH guidelines.

Time (days)	Temperature
	Drug content (%)			Viscosity (cps)			Spreadability
	4 ± 1 °C	25 ± 1 °C	40 ± 1 °C	4 ± 1 °C	25 ± 1 °C	40 ± 1 °C	4 ± 1 °C	25 ± 1 °C	40 ± 1 °C
0	99.87 ± 0.9	99.21 ± 1.2	99.87 ± 2.1	35,276 ± 14	35,276 ± 14	35,266 ± 11	10.76 ± 1.9	10.96 ± 1.1	10.95 ± 1.1
30	99.17 ± 1.1	98.87 ± 1.4	98.12 ± 1.5	35,296 ± 12	35,271 ± 13	35,249 ± 14	10.72 ± 0.8	10.93 ± 1.4	10.76 ± 1.3
60	98.11 ± 1.4	98.11 ± 0.8	98.01 ± 1.3	35,316 ± 10	35,256 ± 15	35,238 ± 14	10.66 ± 1.2	10.92 ± 0.8	10.71 ± 0.8
90	98.02 ± 1.2	97.71 ± 1.5	97.66 ± 1.1	35,282 ± 20	35,242 ± 15	35,233 ± 13	10.71 ± 1.3	10.89 ± 1.1	10.62 ± 0.9