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. 2021 Oct 27;22(21):11584. doi: 10.3390/ijms222111584

Table 1.

Evidence of the AOC of some natural melatonin derivatives.

Actions Ref.
AFMK Hydroxyl radical scavenger.
Radiation protector.
Inhibitor of lipid peroxidation and OS-induced neuronal damage.
Inhibitor of OS induced by Cu(II)-ascorbate mixtures.
ROS scavenger.
RNS scavenger.
Protector against diverse oxidants.
[177,178,179]
[180]
[177,178,179,181]
[113]
[182,183,184]
[185,186,187,188,189]
[183,190,191]
Serotonin Inhibitor of lipid peroxidation.
ROS scavenger.
Fe(II) chelator.
Inhibitor of OH production.
[123]
[121]
[192]
[125]
NAS Neuroprotector.
Antioxidant and anti-aging protector.
Inhibitor of DNA oxidation induced by H2O2 and Cr(III).
Inhibitor of UV-induced cataracts.
Inhibitor of Cu-induced lipoproteins oxidation.
Inhibitor of lipid peroxidation.
Keeper of optimal fluidity of the biological membranes.
[193,194]
[195]
[196,197,198]
[44]
[199,200]
[201,202,203,204]
[205]
6OHM Inhibitor of quinolinic-acid induced neurotoxicity.
Inhibitor of UV-induced OS.
Inhibitor of KCN-induced O2•− production.
Inhibitor of iron-induced lipid peroxidation.
Inhibitor of cyanide-induced OS.
Inhibitor of thiobarbituric acid-induced lipid peroxidation.
[206]
[183]
[207]
[208,209]
[207]
[210]
c3OHM Scavenger of ABTS•+ (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation). [211]
Peroxyl radicals scavenger. [212]
Hydroxyl radical scavenger. [173,212]
Inhibitor of OS induced by Cu(II)-ascorbate mixtures. [113]
5HTP Anti-inflammatory.
Free radical scavenger.
Inhibitor of iron-induced lipid peroxidation.
Inhibitor of Fe/ascorbate-induced oxidation.
Metal chelator.
Inhibitor of UV-induced apoptosis in human monocytes.
[114]
[115]
[116]
[117]
[120]
[119]
5MTA Hydroxyl radical scavenger.
Inhibitor of lipid peroxidation.
Hypochlorous acid deactivator.
Inhibitor of malondialdehyde formation.
Inhibitor of exercise-induced cellular oxidative changes
[212]
[213,214]
[201]
[215]
[216]