Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IC50 values determined on A549 cells for the free PTX, Paclitaxel LANS®, and developed PTX formulations.
| Formulation | Loading (µg/mg of NPs) |
IC50 (ng/mL) |
|---|---|---|
| Free PTX | − | 4.4 ± 0.4 |
| PTX LANS | − | 4.9 ± 0.3 |
| PTX loaded in PMAG-b-PChMA NPs | 50 | 16.6 ± 1.0 |
| PTX loaded in PMAG-b-PChMA NPs | 100 | 25.1 ± 0.9 |
| PTX loaded in PVSAA-b-PChMA-b-PVSAA NPs | 50 | 10.6 ± 0.5 |
| PTX loaded in PVSAA-b-PChMA-b-PVSAA NPs | 100 | 11.3 ± 1.0 |
