Table 1.
Selected miRNAs involved in myogenic differentiation.
| miRNA | Selected Target Factors | Function | Selected References |
|---|---|---|---|
| miR-1 | PAX3, PAX7, HDAC4, and ID1-3 | promotes myoblast differentiation | [50,51,52,53,54] |
| miR-206 | PAX3, PAX7, NOTCH3, IGFBP5, HDAC4, and ID1-3 DNA POLA1 |
promotes myoblast differentiation | [49,50,51,52,53,54,55,57,59] |
| miR-133a/b | cyclin D1, SRF | supports myoblast proliferation, inhibits differentiation | [47,59] |
| miR-27b | PAX3 | promotes myoblast differentiation | [60] |
| miR-486 | PAX7 | promotes myoblast differentiation | [51] |
| miR-181a | HOXA11 | required for terminal stages of myogenic differentiation | [61] |
| miR-214 | N-RAS | promotes myoblast differentiation, limits myoblast proliferation | [59,62,63] |
| miR-17/19 | MRFs | regulates myoblast differentiation | [64] |