Table 3.
AMPs with antibiofilm activity, including the strains and modes of action.
| AMPs | Microorganisms | Mechanism of Action | References |
|---|---|---|---|
| LL-37 | Pseudomonas aeruginosa | Inhibit bacterial adhesion; disruption of cell signaling system | [126] |
| DJK5 and DJK6 | Pseudomonas aeruginosa | Suppress the alarm system | [131,132] |
| 1081 | A series of G+ and G− (Pseudomonas aeruginosa, Escherichia coli, etc.) | Suppress the alarm system; eradication of mature biofilms | [130] |
| Human β-defensin 3 | Staphylococcus epidermidis | Downregulate the expression of binding protein transport genes responsible for biofilm formation | [133,134] |
| 1037 | Pseudomonas aeruginosa | Downregulate the expression of binding protein transport genes responsible for biofilm formation | [135] |
| Nisin A | MRSA | Interfere with the bacterial membrane potential in the biofilm | [125] |
| Esculentin (1–21) | Pseudomonas aeruginosa | Interfere with the bacterial membrane potential in the biofilm | [137] |
| G3 | Streptococcus mutans | Inhibit bacterial adhesion; degrade EPSs | [141] |
| P1 | Streptococcus mutans | Degrade EPSs | [138] |