Skip to main content
. 2021 Oct 29;22(21):11778. doi: 10.3390/ijms222111778

Table 6.

Gene expression profiling of glucocorticoid (GC) producing and target tissue types. (CS: Cushing syndrome, cortisol-producing adrenal adenoma; dex: dexamethasone; #: the munber of Controls).

Sample Type Experiment # of Control # of Dex Treatment/GC Affected DataSet [Refs] Platform
Human tissue bone tissue biopsies from CS patients, before vs. 3 months after surgery 9 9 GSE30159 [53] Affymetrix Human Genome U133 Plus 2.0 Array
Human tissue adrenal cortex, normal tissue vs. GC secreting adenoma 4 4 GSE14922 [51] Agilent-014850 Whole Human Genome Microarray 4 × 44 K G4112F
In vitro human cell line adrenocortical cancer (H295R) cell line, control vs. dex treatment 3 3 GSE64826 [52] Affymetrix Human Gene 1.0 ST Array
In vitro human primary cells osteoblast cell, control vs. dex 6 3 GSE21727 [54] Illumina humanRef-8 v2.0 expression bead chip
In vitro human primary cells osteoblast-like cells (HObs) from bone explant, control vs. dex treatment 6 3 GSE10311 [55] Affymetrix Human Genome U133 Plus 2.0 Array
In vitro human primary cells synovial fibroblasts, control or dex treatment 6 3 GSE37520 [56] Applied Biosystems/University of Birmingham Human RT-PCR array (custom made)
In vitro human primary cells abdominal subcutaneous adipose cells, control vs. dex treatment 3 3 GSE88966 [57] Affymetrix Human Gene 1.0 ST Array
In vitro human primary cells abdominal omental adipose cells, control vs. dex treatment 3 3 GSE88966 [57] Affymetrix Human Gene 1.0 ST Array
In vitro human primary cells epidermal keratinocytes, control vs. dex treatment 2 2 GSE26487 [58] Affymetrix Human Genome U95 Version 2 Array
German Landrace piglet tissue 7-week old purebred piglet hippocampus tissue, control vs. im. dex treatment 20 12 Murani et al., 2021 [74] TruSeqStranded mRNA sample preparation kit; HiSeq 2500 instrument
German Landrace piglet tissue 7-week old purebred piglet hypothalamus tissue, control vs. im. dex treatment 20 12 Murani et al., 2021 [74] TruSeqStranded mRNA sample preparation kit; HiSeq 2500 instrument