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. 2021 Oct 31;22(21):11835. doi: 10.3390/ijms222111835

Table 1.

LD50 and LC50 results for imidacloprid in honey bees (Apis mellifera).

Oral LD50a
(ng Per Bee)
Contact LD50 (ng Per Bee) Oral LC50a (ppm) Test Period Honey Bee Tested Areas Hours Reference
adults NA 40 NA NA NA USA 24 [37]
5.4 (5.2–1.6) 23.8 (22.3–25.3) NA NA Apis mellifera mellifera France 24 [24]
6.6 (5.1–8.1) 15.1 (11.9–18.3) Apis mellifera caucasica
4.8 (4.5–5.1) 24.3 (22.0–26.6) NA NA Apis mellifera mellifera 48
6.5 (4.7–8.3) 12.8 (9.7–15.9) Apis mellifera caucasica
41 NA NA Jul-99 NA Germany I 72 [26]
20 104 (83.0–130) Jul-99 The Netherlands I
81 61.0 (26.0–90.0) May-00 Germany II
81 50.0 (9.1–71.0) May-00 United Kingdom I
81 42.0 (20.0–59.0) May-00 Germany III
81 42.9 (34.6–53.2) May-00 Germany IV
81 74.9 (61.8–90.9) Jul-00 Germany V
57 ± 28 NA NA NA NA France 48 [25]
37 ± 10 72
37 ± 10 96
3.7 (2.6–5.3) 81 (55.0–119.0) NA NA NA UK 48 [2]
> 21.0 230.3 Netherlands
40.9 nt Germany
11.6 (7.3-18.3) 242.6 (173.3–353.4)
21.2 (15.0-29.6) 59.7 (39.1–92.7)
NA 17.9 (9.2–31.5) NA Jun to Sep-99 NA USA 24 [38]
30.6 NA NA NA NA France 48 [39]
25.4 ± 22.8 NA NA NA NA France 48 [40]
118.74 NA NA NA NA Italy 24 [23]
90.09 48
69.68 72
NA 29 0.003 NA NA Egypt 24 [27]
26 0.0006 48
larvae 4170 (2960–5850) NA 138.84 (98.20–196.30) NA NA USA. 72 [28]
1400 NA NA NA Taiwan 268 [41]