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. 2021 Oct 28;22(21):11699. doi: 10.3390/ijms222111699

Figure 5.

Figure 5

Photos of hematoxylin and eosin, periodic acid–Schiff stains, and electron microscopy of wild-type (WT) and CR6-interacting factor-1 knockout (CRIF1-KO) mouse kidneys. WT-unilateral ureteral obstruction (UUO) kidneys showed an increase in tubular injury score compared with non-UUO kidneys. CRIF1-KO-UUO kidneys showed an increase in tubular injury score compared with WT-UUO kidneys. Although CRIF1-KO kidneys showed severe mitochondrial injury, UUO did not significantly alter the mitochondrial morphology in WT kidneys. * p < 0.05, WT-sham vs. WT-UUO; # p < 0.05, WT-UUO vs. CRIF1-KO-UUO.